Zofran is an oral medication that is taken either alone or with other drugs to prevent vomiting and nausea caused by radiation therapy or chemotherapy. It works by blocking serotonin that results in vomiting.
How to Use Zofran Correctly
To prevent nausea caused by chemotherapy, you need to take this medicine orally, 30 minutes before this treatment starts. To prevent this symptom caused by your radiation treatment, take Zofran orally 1-2 hours before it starts. Those patients who want to prevent nausea after any surgery should use this medication orally 1 hour before their surgical procedures. It’s possible to take this drug both with and without food, but doctors usually advise their patients to avoid eating before surgeries, radiation and chemotherapy. Sometimes, Zofran can be taken 3 times a day for a few days after radiation treatment or chemotherapy. If you need to use it on a specific prescribed schedule, take doses regularly to get its full benefit. The right dosage is always based on individual response and medical condition. For children, their doses are adjusted based on their body weight and age. If you have any liver problems, your maximum daily dosage is 8 mg.
Mild and Serious Side Effects
There are some adverse effects that can be caused by the intake of Zofran, including:
Dizziness and headaches;
Drowsiness and lightheadedness;
Unusual tiredness and constipation.
If any of these symptoms get worse, you should notify doctors at once. Most patients who undergo this treatment don’t experience any serious side effects that are very unlikely:
Muscle stiffness and spasms;
Vision changes and stomach pain;
Severe dizziness and fainting;
Chest pain and allergic reactions;
Irregular, fast or slow heartbeats.
If you have any of these troubling signs, go to the hospital as soon as you can.
Important Zofran Precautions
Before you start taking this drug, talk to doctors, especially if you have any allergies to medications. Tell them everything about your medical history, including liver and kidney problems, irregular heartbeats, intestinal and stomach conditions, etc. In rare cases, the intake of Zofran can make some patients feel drowsy or dizzy, so they should avoid driving and doing other things. It’s also necessary to limit the consumption of alcoholic beverages. Older patients are more sensitive to the side effects caused by this medication, especially QT prolongation.
Dangerous Drug Interactions
There are some medications that shouldn’t be combined with Zofran because of possible health risks and drug interactions. Don’t take this medicine with tramadol, macrolide antibiotics, pills that affect heart rhythms, etc. Make a full list of other non-prescription and prescription meds that you’re taking and don’t forget about vitamins, minerals and herbal supplements.