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    Nowadays people suffer from a plenty of different diseases which become a great obstacle to a happy life. Abnormal muscle fatigue syndrome is one of the most widespread illnesses. However, there is an effective remedy called Mestinon, which is a good helper in this and many other problems.

    It possesses the following pharmacologic effects:

    bullet_ball_blue It is an anticholinesterase remedy;
    bullet_ball_blue It increases the action of acetylcholine;
    bullet_ball_blue The drug improves neuromuscular transmission;
    bullet_ball_blue It increases gastrointestinal motility;
    bullet_ball_blue Improves the bladder tone, bronchial secretion of glands;
    bullet_ball_blue However, it causes bradycardia, slight miosis, light spasm of accommodation.

    What Diseases Will Disappear after the Intake of Mestinon

    bullet_ball_blue Myasthenia and myasthenic syndrome;
    bullet_ball_blue Postoperative intestinal atony, disease of atonic constipation, bladder atony;
    bullet_ball_blue Some movement disorders caused by trauma;
    bullet_ball_blue Flaccid paralysis;
    bullet_ball_blue Permanent effects of polio, encephalitis;
    bullet_ball_blue Ingringement of emptying the bladder as a result of gynecological operations and childbirth;
    bullet_ball_blue Suspension of muscle relaxation during general anesthesia;
    bullet_ball_blue Overdose of muscle relaxants;
    bullet_ball_blue Intoxication by anticholinergic drugs (if peripheral symptoms present).

    Contraindications and Side Effects

    As for contraindications, they are the following:

    bullet_ball_blue Hypersensitivity;
    bullet_ball_blue Prior intake of muscle relaxants;
    bullet_ball_blue Iritis;
    bullet_ball_blue Bronchial asthma;
    bullet_ball_blue Obstructive ileus;
    bullet_ball_blue Severe spasm of gastrointestinal tract, urinary or biliary tract;
    bullet_ball_blue Myotonia;
    bullet_ball_blue Parkinson’s disease;
    bullet_ball_blue Postoperative shock;
    bullet_ball_blue Period of lactation;
    bullet_ball_blue Pregnancy.

    If you have some of these illnesses or conditions, you may speak with your doctor about the recommended doses.

    As for side effects, they are quite rare. However, it is necessary to know what feelings can appear during the intake of this drug. So the possible adverse reactions are the following:

    bullet_ball_blue Nausea, vomiting, light diarrhea, stomach cramps;
    bullet_ball_blue Enlarged peristalsis;
    bullet_ball_blue Hypersecretion of glands;
    bullet_ball_blue Hard salivation;
    bullet_ball_blue Frequent urination;
    bullet_ball_blue Low blood pressure;
    bullet_ball_blue Bradycardia;
    bullet_ball_blue Muscle twitching;
    bullet_ball_blue Skin rashes (due to the content of bromine in the drug).

    Important Special Instructions and Some Important Facts

    It is necessary to decide on the time of Mestinon intake according to the period of the physical activity of the patient. It should coincide with the maximum effect of the remedy. The absence of an expected effect of treatment can be a consequence of Mestinon overdose.

    During the treatment with Mestinon you should not use ethanol. You should be careful when driving and other activities which require high level of concentration and fast reactions. Atropine weakens the effect of Mestinon (relative bradycardia, hypersecretion). Moreover, it enhances the effect of depolarizing muscle relaxants, different barbiturates and morphine derivatives. Such ingredients as quinidine, procainamide, local anesthetics, some tricyclic antidepressants, antiepileptic and all the antiparkinsonian drugs reduce Mestinon action.