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    Isoniazid is a medication taken with other drugs to treat TB, or tuberculosis infections. Basically, it’s an effective antibiotic that works by stopping and preventing the growth of harmful bacteria, so it should be used to treat only bacterial infections, because its misuse or unnecessary use results in reduced effectiveness.

    How to Take Isoniazid Correctly

    It’s advisable to use this medicine orally on your empty stomach (1-2 hours before any meal). The right dosage is always based on such basic factors as your weight, age, individual tolerance, etc. You need to take Isoniazid at evenly spaced intervals and at the same time of the day. Skipping regular doses and stopping this treatment too early may let bacteria keep growing. Sometimes, doctors prescribe their patients vitamin B6 to help them prevent specific side effects, such as nervous issues, while taking Isoniazid. It may interact with specific food products that contain histamine and tyramine, including red wine, cheese and certain fish types.

    Its use may increase blood pressure and cause other unwanted symptoms that should be reported to doctors immediately. Besides, when taking any antacids that contain aluminum, you need to use Isoniazid 1 hour before their consumption.

    Mild and Severe Adverse Effects

    There are some side effects caused by this treatment, including stomach ulcers, vomiting and nausea. However, most patients who take Isoniazid don’t feel any discomfort. You need to call your physician once you notice the following serious and rare adverse effects:

    bullet_ball_blue Swollen or painful joints;
    bullet_ball_blue Tingling or numbness of legs and arms;
    bullet_ball_blue Sudden urine changes and increased urination;
    bullet_ball_blue Increased thirst and allergic reactions;
    bullet_ball_blue Easy bleeding and bruising;
    bullet_ball_blue Unexpected vision changes and signs of new infections;
    bullet_ball_blue Mood and mental changes.

    Basic Isoniazid Precautions

    Before taking this medication, you need to inform doctors whether you have any allergies to its ingredients. Moreover, they should know about other serious health conditions that you have, including liver and kidney problems, alcohol abuse, diabetes, HIV infections, past serious reactions from Isoniazid, recent childbirth, tingling and numbness of legs and arms and so on. Alcoholic beverages are responsible for increasing the risk of liver problems, so you should avoid them when undergoing this treatment. This medicine is also contraindicated with live bacterial vaccines and immunizations, so they should be avoided.

    Drug Interactions

    Don’t combine Isoniazid with specific medications because of a possible risk of dangerous drug interactions. For example, this medicine shouldn’t be combined with some azole antifungals, MAO inhibitors, SSRIs and others. That’s why you need to keep a list of other over-the-counter and prescription pills that you’re using in addition to herbal supplements, minerals and vitamins. Doctors should be well informed about any of them.


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