Dulcolax is a laxative (derivative of diphenylmethane). As a local laxative with an antiresorptive effect, after the process of hydrolysis in the colon, bisacodyl increases the secretion of water and electrolytes in the large intestine. It also accelerates and increases its peristalsis. This leads to invigoration of the defecation act, decreases the time of evacuation and leads to softening of the stool. This remedy is quite effective and able to solve many delicate problems.
The time of laxative effect development of the remedy is from 6 to 12 hours.
It is used as an effective drug in the following cases:
Constipation due to hypotension of the colon (including chronic);
Preoperative preparation, postoperative treatment, preparation for instrumental and roentgenological studies, medical conditions requiring facilitation of defecation.
Rules of Intake and Dosage
It is desirable to take Dulcolax in a right way if you want to have a good result without any possible side effects. The pills are taken orally together with a sufficient amount of liquid.
When suffering from constipation, adults and children older than 10 should take 1-2 pills (5-10 mg). 4-10-year-old children should take 1 pill (5 mg). To get a laxative effect early in the morning, it is necessary to use the drug the night before.
Dulcolax should not be taken with products that reduce acidity in the upper GI tract, such as milk, proton pump inhibitors or antacids for avoidance of premature dissolution of the enteric coating. When getting ready for examinations, pre- and post-operative treatment, medical conditions that require defecation, Dulcolax should be taken under thorough medical supervision. It is necessary to take 2 pills in the evening before for the day of examination and 2 pills at night before a surgery. It is possible to take pills a in combination with suppositories. For adults, it is necessary to use 1 suppository in the morning in addition to the dose of 2-4 pills.
Side Effects and Contraindications
Digestive system: severe discomfort, nausea, vomiting, spastic pain in the abdominal area, diarrhea, colitis;
Possible reactions of hypersensitivity from the immune system, including severe angioedema and anaphylaxis.
Severe obstructive bowel disease;
Acute diseases connected with the abdominal cavity, including appendicitis;
Strong inflammatory bowel diseases;
Severe abdominal pain connected with nausea and vomiting that may be an important symptom of a more serious condition;
Children younger than 4 years old;
Hypersensitivity to bisacodyl or excipients.
During pregnancy and breastfeeding, the drug can be taken only after consultation with your doctor, though no harmful reactions were revealed so far.